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Background/Introduction: Gastric carcinoma is the second most common digestive tract cancer and the third leading cause of cancer-related death worldwide. In Nigeria, it is a major contributor to cancer-related mortality. There is a recent interest in studying the benefits of targeted therapy in its management using anti-HER-2 monoclonal antibody because of the increased overall survival when used in combination with chemotherapy. Aim and Objectives: The objective of this study was to determine the frequency of HER-2 over-expression in gastric carcinomas in Lagos, comparing it with known pathologic and prognostic factors and also with similar available studies. Materials and Methods: The clinical data were retrieved from two laboratories in Lagos (Lagos University Teaching Hospital and The Specialist Laboratories) involved in the study. Haematoxylin & Eosin slides were made from the patients’ formalin fixed paraffin embedded blocks and were reviewed to confirm diagnosis and pathological parameters. HER-2 over expression was assessed by staining with anti-HER-2 antibody. The data was analysed using SPSS 16 to correlate HER-2 over-expression and the pathological features of the carcinomas.
Surnames and Other Names:
DR ONYEKWELU VINCENT IKENNA
Resource Type:
dissertation
Faculty:
PATHOLOGY
“THE DISTRIBUTION AND SEVERITY OF ATHEROSCLEROSIS IN ADULT NIGERIANS: A 12 MONTH PROSPECTIVE AUTOPSY STUDY”.
Surnames and Other Names:
DR ORAH NNAMDI O
Resource Type:
dissertation
Faculty:
PATHOLOGY
A STUDY OF TUMOURS OF THE EYE AND OCULAR ADNEXA SEEN AT THE UNIVERSITY COLLEGE HOSPITAL, IBADAN, NIGERIA BETWEEN JANUARY 2003 AND DECEMBER 2012
Surnames and Other Names:
DR PETER OLUFEMI OLOGUNAGBA
Resource Type:
dissertation
Faculty:
PATHOLOGY
CHARACTERIZATION OF THE BETA GLOBIN GENE AMONG SICKLE CELL ANAEMIA PATIENTS IN ZARIA
Surnames and Other Names:
DR SANI AWWALU
Resource Type:
dissertation
Faculty:
PATHOLOGY
SERUM LEVELS OF CARDIAC TROPONIN T AND CREATINE KINASE MB FRACTION IN PATIENTS WITH ACUTE ISCHAEMIC STROKE
Surnames and Other Names:
DR SULEIMAN, HAFSATU MAIWADA
Resource Type:
dissertation
Faculty:
PATHOLOGY
HISTOPATHOLOGICAL PATTERN OF LIVER BIOPIES IN ZARIA; A TEN YEAR RETROSPECTIVE ANALYSIS [2004 2013]
Surnames and Other Names:
DR USMAN BELLO
Resource Type:
dissertation
Faculty:
PATHOLOGY
DETERMINANTS OF ANTIRETROVIRAL THERAPY ADHERENCE AMONG HIV - INFECTED ADOLESCENTS ATTENDING UNIVERSITY OF ABUJA TEACHING HOSPITAL, GWAGWALADA, ABUJA.
Surnames and Other Names:
DR EKOP ENO ELOHO
Resource Type:
dissertation
Faculty:
PAEDIATRICS
SKIN DISEASES, RISK FACTORS AMONG PRIMARY SCHOOL CHILDREN AND HEALTH SEEKING BEHAVIOUR OF THEIR PARENTS/GUARDIANS IN UMUAHIA SOUTH LOCAL GOVERNMENT AREA OF ABIA STATE
Surnames and Other Names:
DR EWURUM ODOCHI
Resource Type:
dissertation
Faculty:
PAEDIATRICS
BACTERIAL AETIOLOGY, CLINICAL MANIFESTATIONS AND FACTORS ASSOCIATED WITH NEONATAL SEPSIS AT AMINU KANO TEACHING HOSPITAL, KANO, NIGERIA.
Surnames and Other Names:
DR HADIZA ASHIRU USMAN
Resource Type:
dissertation
Faculty:
PAEDIATRICS
EVALUATION OF MALARIA ENDEMICITY IN EGOR LGA, EDO STATEUSING ASYMPTOMATIC MALARIA PARASITAEMIA AND SPLEEN RATE IN APPARENTLY HEALTHY SCHOOL CHILDREN
Surnames and Other Names:
DR IFEBI EMEKA AUGUSTINE
Resource Type:
dissertation
Faculty:
PAEDIATRICS
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