Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder of childhood characterised by a persistent pattern of inappropriate inattention, motor hyperactivity and impulsivity. While ADHD is mostly diagnosed in the preschool and school age period, research shows that features of the disorder persist throughout the lifespan. The disorder tends to be missed or misdiagnosed in adolescents partly due to its often atypical presentation in this age group, often with considerable academic and social consequences. Adolescents have been shown be quite reliable informants about their own experiences, and it is possible that the development and use of self-report instruments to screen for ADHD among them would be crucial to detecting and managing the disorder in this age group. Aim and Objectives This study aimed at examining the internal consistency and validity coefficients of the Current ADHD Symptoms Scale Self-Report (CSS-SR) in a bid to ascertain its usefulness among a group of adolescents in senior secondary schools in Ibadan North Local Government Area of South-West Nigeria. Its specific objectives also included determining the most suitable cut-off point for the use of the instrument among adolescents in the study environment, and examining the effects of sociodemographic variables on its screening ability. Methodology One thousand four hundred and eighty-four students in Senior Secondary class 1 were selected from a list of secondary schools in Ibadan North Local Government Area, using a multi-stage sampling method. The first stage involved administering the 18- item CSS-SR and a socio- demographic questionnaire to all the students, who filled them individually. Students who screened positive for ADHD, along with 15% of those who did not score up to a cut-off of 6 on either of the CSS-SR subscales, were interviewed by the researcher in the second stage of the study. This stage involved the use of the ADHD supplement of the Schedule for Affective Disorders and Schizophrenia for School-aged Children (KSADS). Results The CSS-SR was demonstrated to have good internal consistency, with an overall Cronbach’s α of 0.86. It also showed impressive validity coefficients, with a sensitivity and specificity of 0.86 and 0.86 respectively using a threshold score of 6. This cut-off score was also demonstrated to show optimal discriminatory ability for diagnosing and ruling out ADHD using the Receiver operating (ROC) curve. However none of the sociodemographic variables examined showed any significant effect on the screening ability of the CSS-SR. Conclusion The CSS-SR is a relatively brief self-report instrument which has been used to screen for ADHD among adults. This study demonstrates desirable properties it possesses which make it suitable for the detection of the disorder among adolescents in Ibadan, South West Nigeria. Recommendations The CSS-SR can be administered with relative ease and accuracy. Its use among secondary school students would contribute greatly to the detection and subsequent management of ADHD in this population of young people.