Postpartum depression is the most prevalent postpartum mental health problem. Risk factors for postpartum depression include psychosocial stressors. One of these psychosocial stressors could be intimate partner violence. Postpartum depression is associated with early breastfeeding discontinuation, bonding impairment, thoughts of harming the baby, and constitutes huge burden on the family members and the society at large. Intimate partner violence (IPV) is a public health issue in both developed and developing countries. Co-occurrence of intimate partner violence and postpartum depression is considered a deadly co morbidity because it can increase the risk of homicide and suicide. There is dearth of research on intimate partner violence and postpartum depression in Nigeria. AIM The aim of this study was to determine the rate of IPV, PPD and the relationship between intimate partner violence and depression among postnatal women attending postnatal and infant welfare clinics of LAUTECH Teaching Hospital, Osogbo. METHODS A descriptive cross-sectional study was conducted among 220 postpartum women who attended postnatal and infant welfare clinics of LAUTECH Teaching Hospital in Osogbo using Composite Abuse Scale (CAS), Edinburgh Postnatal Depression Scale (EPDS) and Socio-demographic questionnaire. Respondents that were found to be EPDS positive as well as 10% of EPDS negative respondents were further assessed with Mini International Neuropsychiatric Interview (MINI) (depression subscale) to diagnose depression. RESULTS Majority of the respondents were of Yoruba ethnicity and currently in a monogamous relationship. Two third of the respondents were Christians and more than half of the respondents were within the age range 30-39 years. The mean age of the respondents was 30.12(±4.76). The prevalence of intimate partner violence was 26.8%. The prevalence of postpartum depression was 9.5% using MINI. Among those that experienced IPV, only 28.8% sought help and most used informal strategies. When depressed and non-depressed respondents were compared, statistically significant differences were observed between the groups on number of children (p= 0.039), support from husband during pregnancy (p = 0.010), support from husband’s relatives during pregnancy (p = 0.036) and witnessing sexual abuse while growing up (p = 0.046). Respondents that experienced intimate partner violence were five times as likely to have postpartum depression compared to those that did not experience IPV. There were significant positive correlations between postpartum depression and intimate partner violence and age of partner (r= 0.499, p= 0.01 and 0.156, p = 0.05 respectively). With respect to IPV in respondents, there were significant positive correlations with number of wives and number of children (r= 0.154, p= 0.05 and 0.139, p= 0.05 respectively). Logistic regression showed that intimate partner violence independently predicted postpartum depression in respondents (OR 4.799, CI 1.844-12.493). CONCLUSION Postpartum depression was significantly higher among women that experienced intimate partner violence. This observation has implications for mental health of women, therefore, any woman with suspected postpartum depression should be asked about IPV as this could be a pointer to IPV and the effect of the co-morbidity is grave for mother and child. This study is useful in providing part of a data base in Nigeria that may be important for advocating policy reviews and development to protect the rights of women. More research is needed to explore the relationship between intimate partner violence and postpartum depression using a longitudinal approach to allow causal inference.