Background: Duration of labour can affect foeto-maternal outcome and the hazards associated with prolonged labour are well known. Active management of labour reduces number of prolonged labour without having adverse effects on the mother or fetus. Hyoscine butylbromide have been used to shorten the first stage of labour with varying degrees of success. Objectives: To determine the effect of hyoscine butylbromide on the duration of the active phase of first stage of labour at FMC Katsina. Methods: The study was a prospective double blinded randomized study which was carried out over a period of 8 months. One hundred and twenty patients in active phase of labour at term at FMC Katsina were recruited and randomly assigned into two groups and were administered either hyoscine butylbromide or placebo to compare the duration of labour in both groups. Outcome measures included duration of first, second and third stages of labour, fetomaternal vital signs, maternal side effects, APGAR scores and NICU admission.