Aims: Burn injuries present major challenges to the patients and the burn care providers. Cost is one of the most prominent aspects of these challenges. This is heightened by the high prevalence of poverty in our Society and inadequate funding of the Health Sector by all tiers of Government. The Cost Implication of Burn Care is a prospective study of the early and late costs incurred in the management of burns. Methods: Patients presenting with acute burn injuries or post-burn complications at the National Orthopaedic Hospital, Igbobi-Lagos between June 2007 and May 2008 were studied. Biodata and details of treatment related to cost were recorded. The data were updated at intervals as necessary for each case during the study. Results: Fifty-two patients were seen during the study period. The average cost per day was N8,855.00, while the average total cost of early treatment was N209,805.7 ±77,397.2, with a range of N14,470 to N2,206,950. Dressings accounted for 51.6% of the total early cost, in-patient charges were 18.5%, while surgery accounted for 4.3%. The average cost of late treatment was N208,761.6 ±169,959.3, with a range of N13,050 to N738,940. Thirty-five percent of the total late cost was spent on surgery, 33.5% on in-patient charges, and 5.6% on dressings. The unquantifiable costs included job losses, lost man hours and social costs. Conclusions: The study showed that the monetary and non-monetary costs of burn care were significant. Suggestions on cost reduction were made. The role of burn prevention was also emphasized.