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SPOT URINE PROTEIN/CREATININE RATIO VERSUS 24 HOUR URINARY PROTEIN IN PREDICTING ADVERSE PREGNANCY OUTCOME IN PRE-ECLAMPSIA

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Supervisor: Prof. OUJ umeora
Faculty: OBSTETRICS AND GYNAECOLOGY
Institution of Training: FEDERAL TEACHING HOSPITAL, ABAKILIKI
Year: 2017

Abstract

Background: Urinalysis for proteins is one of the important fundamental investigations performed to diagnose preeclampsia, monitor the severity of the disease and help predict adverse pregnancy outcomes. Although the 24 hour protein quantification is the gold standard, it is time consuming, cumbersome to perform and urine collection occasionally can be incomplete. Recently, spot urine protein/creatinine ratio has been used to quantify urinary protein, with value comparable with the 24 hour urine estimation. Estimation of the ratio of spot urine protein to creatinine that best predicts maternal and fetal complications will aid in clinical management. Objective: This study was designed to evaluate the correlation of spot urine protein to creatinine ratio (SUPCR) with 24 hour urine estimation and the relationship with adverse pregnancy outcomes in preeclamptics. Method: This was a prospective cross sectional study to determine the place of admission spot urine protein creatinine ratio and admission 24 hour urinary protein values in predicting adverse pregnancy outcome in pregnant women with preeclampsia at the Federal Teaching Hospital Abakaliki (FETHA). Data analysis was done using IBM-SPSS software (version 20, Chicago II, USA).

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