BACKGROUND: Iron deficiency anaemia is the most common cause of anaemia in pregnancy in developing countries. Iron deficiency with or without causing maternal anaemia could have adversely affect pregnancy. The iron stores in the body can be estimated by assaying the serum ferritin levels as this is the best non-invasive method and closely reflects that gotten form a bone marrow aspiration. When there is infection, hyperthyroidism or malignancy, the serum ferritin levels are increased and may not reflect a situation of iron deficiency even when it is present. AIM: The aim of this study was to determine the relationship between serum ferritin levels of women in spontaneous labour and their pregnancy outcome. METHODOLOGY: This study was a cross-sectional analytic study conducted at the University of Benin Teaching Hospital, Benin City. Two hundred and fifty (250) women in labour who met the inclusion criteria and gave informed consent were enrolled into the study. Blood samples were taken from these women for serum ferritin and Packed Cell Volume estimation. Relevant data was collected and filled into the data extraction sheet with analysis done thereafter.