Background Over 285 million people in the world are visually impaired, of whom 39 million are blind and 246 million have low vision. About 90% of the world’s visually impaired lives in developing countries. In Nigeria, based on figures from the National Blindness and Visual impairment survey, it is estimated that approximately 800, 000 individual have low vision. Objective To determine the profile of low vision patients in University of Nigeria Teaching Hospital, Ituku-Ozalla (UNTH) with a view to proffering measures for appropriate, affordable and accessible low vision service. Materials and Methods: This was a cross-sectional study of all new consecutive low vision patients seen at the eye clinic of University of Nigeria Teaching Hospital Ituku-Ozalla. All patents with low vision were evaluated by the researcher and the findings entered on a research protocol. Data were analyzed using descriptive statistics to generate frequency and percentage distributions and analytical statistics to test for significance of observed inter-group differences. In all comparisons statistical significance was indicated by p<0.05. Results: A total of 197 patients were seen. There were more males (M) than females (F) in the study with an M:F of 1.6:1. The mean age was 39.3 years (SD) ±22.9.The main causes of low vision in the study population were glaucoma (36.0%), oculocutaneous albinism (14.7%), amblyopia (8.1%), and age related macular degeneration (7.6%). The mean presenting distant VA was logMAR 1.1 (95% CI), while the mean near VA was logMAR 1.0 (6/60, 20/200). 1 After optical low vision assessment 57.9% had improved vision. The mean distant VA was logMAR 0.8 which was statistically significant (p≤0.0.005). Near vision after optical assessment improved with a mean of logMAR 0.8, which was statistically significant (p≤0.005).