Objectives: To determine the prevalence of cataract and identify factors affecting the uptake of cataract surgery in Ukpor, Nnewi-South Local Government Area, Anambra State. Materials and Method: This is a population-based cross-sectional study. Using a multi-stage cluster random sampling technique with probability proportional to size, adults aged 50 years and above were recruited. Data was obtained and analyzed using quantitative and qualitative methods. An interviewer administered semi-structured pretested questionnaire on biodata, knowledge of cataract, health seeking behavior, preferred treatment method and factors affecting the uptake of cataract surgical services was used. Ocular examination included visual acuity measurement, anterior and posterior segments examination. The lens was examined and graded using the Mehra and Minassian lens grading system. Focus group discussion (FGD) was also conducted. Results: Six hundred and thirty-six persons comprising 249 (39.2%) males and 387(60.8%) females were studied. Three hundred and ninety-five persons (62.1%) had cataract in at least one eye; 14 (2.2%) persons bilaterally blind and 60 (9.4%) persons had operable cataract. Only, 106 (16.7%) persons had had intervention for cataract. The overall prevalence of cataract (operated and unoperated) was 64.9% (95% CI: 53.1– 76.6%). Males had a higher prevalence of cataract (P=0.0079), while females had a higher prevalence of cataract blindness (P=0.412). Factors affecting the uptake of cataract surgery were cost 39 (65.0%), fear of blindness 37 (61.7%), and poor outcome of conventional cataract surgery 35 (58.3%). Factors motivating people to seek cataract surgery were awareness of good service points 19 (26.0%), poor vision 17 (23.3%), good surgical outcome 13 (17.8%) and instalment payment mode 11 (15.1%). Reason for opting for couching were fear of surgery 16 (42.1%), cost 10 (26.3%), and fast treatment method 9 (23.7%).