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PREVALENCE AND RISK FACTORS FOR HISTOLOGICAL CHORIOAMNIONITIS AMONGST HIV POSITIVE PREGNANT WOMEN AND ITS ASSOCIATION WITH MOTHER-TO-CHILD TRANSMISSION OF HIV IN A NIGERIAN POPULATION

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Supervisor: PROFESSOR A. S. SAGAY, DR GODWINS ECHEJOH
Faculty: OBSTETRICS AND GYNAECOLOGY
Institution of Training: JOS UNIVERSITY TEACHING HOSPITAL
Month: 10
Year: 2017

Abstract

Background: HIV/AIDS is a global problem of frightening proportions. More than 95% of HIV infected individuals live in the developing world, predominantly in subSaharan Africa with mother to child transmission of HIV being the commonest cause of paediatric HIV/AIDS. Chorioamnionitis is an important risk factor for vertical transmission of HIV/AIDS. Objective: To determine the number of HIV positive women who have histological chorioamnionitis, the impact of various variables such as age, parity, gestational age, sexual intercourse, previous history of chorioamnionitis, history of prolonged rupture of membrane, mode of delivery, number of vaginal examinations etc on the prevalence of chorioamnionitis and to determine the number of babies of women with histological chorioamnionitis who develop MTCT of HIV Methods: It was a cross-sectional study. HIV positive parturients were interviewed, examined and had their placenta examined histologically for chorioamnionitis. Data regarding HIV was also retrieved from their hospital records and their babies were followed up to determine if they have been infected at 6 and 24 weeks.

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