BACKGROUND: Polycystic ovary syndrome (PCOS) is a very common gynaecological endocrinopathy with associated ovulatory dysfunction and infertility. Hyperinsulinemia and hyperandrogenism are at the root of the syndrome. By identifying those with hyperinsulinemia and abnormal glucose tolerance (AGT) and offering appropriate therapy, fertility can be restored. OBJECTIVE: To determine the prevalence of AGT in women with PCOS , attending the Human Reproduction Research Programme/Invitro Fertilisation (HRRP/IVF) Centre, of the University of Benin Teaching Hospital, and to examine the associated risk factors. METHOD: It was a prospective case control study involving a total of 180 women. All of them attending HRRP/IVF centre of UBTH, for infertility management. Ninety of them constituted PCOS group while the remaining 90 formed the control group. The 75gm Oral glucose tolerance test was administered to women in both groups.