Background: Postdates pregnancy is one of the commonest obstetric conditions and is associated with significant risk of perinatal morbidity and mortality. The aetiology is not clearly understood. However, placental senescence with increasing uteroplacental insufficiency and fetal hypoxemia have been proposed to explain the risk of stillbirth in prolonged pregnancy. The management of uncomplicated postdated pregnancy beyond 41 weeks is still debated in modern obstetrics. Doppler velocimetry has been used extensively for fetal surveillance and has been shown to improve fetal outcome in high-risk pregnancy associated with uteroplacental insufficiency. Objectives: To determine the predictive value of cerebro-placental ratio (CPR), i.e. the ratio between middle cerebral artery and umbilical artery pulsatility indices, and best Doppler index for adverse perinatal outcomes in women with postdates pregnancy. Research Methods: A prospective cohort study was conducted on 212 low-risk pregnant women beyond 40 weeks’ gestational age at Aminu Kano Teaching Hospital, Kano in the period between November 2017 to April 2018. Doppler waveform analysis of the pulsatility indices of middle cerebral artery, umbilical artery and cerebro-placental ratio, in addition non-stress tests(NST) and ultrasonography assessment of amniotic fluid index(AFI), were performed on the consented women. They were divided into two groups based on the presence or absence of adverse perinatal outcome defined as: meconium stained liquor, meconium aspiration syndrome, composite fetal outcome, low Apgar score, perinatal asphyxia, caesarean section for suspected fetal distress, and perinatal death outcomes.