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PENTAZOCINE VERSUS COMBINED PENTAZOCINE AND DICLOFENAC FOR PAIN RELIEF IN THE FIRST 24 HOURS AFTER CAESAREAN SECTION: A RANDOMIZED CONTROLLED STUDY

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Supervisor: PROF OUJ UMEORA, DR LO AJAH
Faculty: OBSTETRICS AND GYNAECOLOGY
Institution of Training: FEDERAL TEACHING HOSPITAL, ABAKILIKI
Year: 2016

Abstract

BACKGROUND Pain is one of the important outcomes of caesarean section. Its management still remains a challenge in a low resource setting like ours. The addition of diclofenac to pentazocine provides effective and safe postoperative analgesia. AIM To compare the efficacy of intramuscular pentazocine only and combined intramuscular pentazocine with diclofenac as pain relief within 24 hours after caesarean section. METHODOLOGY A total 146 parturient women who had uncomplicated caesarean section and live babies at the Federal Teaching Hospital Abakaliki were randomly grouped using computer generated numbers into pentazocine placebo group and pentazocine diclofenac group. The pentazocine placebo group received pentazocine 30mg only analgesic every 4 hours for 24 hours and 3ml of water for injection as placebo 12hrly for 24 hours while the pentazocine diclofenac group women received pentazocine 30mg every 4 hours and diclofenac 75mg every 12 hours all for 24 hours. The level of pain control was assessed using visual analog scale (VAS) at 1, 2, 6, 12, 18, 24 hours. The patient satisfaction and side effects of the drugs were also documented. DATA ANALYSIS The information obtained were entered into a predesigned data sheet. The data was analyzed with Statistical package for Social Science (IBM SPSS statistics) version 22.0. Categorical variables were analyzed using chi square. Means and standard deviation (SD) were calculated for quantitative variables, and the difference between two independent groups was compared using independent sample t-test. The level of significance was set at < 0.05.

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