Introduction: Urethral reconstruction with substitute material is required for the repair of complex hypospadias and acquired urethral stricture disease. The aim of surgical reconstruction for urethral stricture is to provide an adequate calibre, compliant and stable urethra. The use of oral mucosa graft as donor tissue in urethral reconstruction consists of autologous transplantation of non-keratinized oral mucosa to the urethra for use in the repair of a variety of urethral defects. The objective of the study was to evaluate the immediate and short term outcome of the use of oral mucosa grafts for urethral reconstruction in patients with long-segment anterior urethral stricture disease. Outcome parameters measured during the study included; changes in urine flow rate pre- and postoperatively, donor site and recipient site complications. Patients and Methods: A prospective study of 28 consecutive male patients who presented with long-segment anterior urethral strictures. They all had oralmucosa graft urethroplasty and the outcomes were analyzed Results: The mean age at presentation was 45.4 + 13.2 years with a range of 14-69 years. The patients presented late with complications (acute urine retention and other complications such as perineal fistulae) in 25 (89%). The mean duration of symptoms at presentation was 60.4 + 56.3 months and a range of 3-240 months. The cause of urethral stricture in the patients was poorly treated urethritis in 22 (78.5% ) , however, in 5 patients ( 17.9%) it was due to urethral catheterization while urethral trauma was the cause in one patient (3.5%). The strictures were located in the bulbar in 14 (50%) and penobulbar urethra in 12 (43%) while in 2 patients (7%) the strictures were located in the penile urethra. The most frequent oral mucosa graft donor site complications were pain in 9 (32%), and haematoma in 4 (14.3%) and these resolved before discharge. There was no mortality or any major recipient site complication. Stricture recurrence was observed in 2 (7) of the patients within the period of follow -up. The pre-operative peak urine flow rate was 4.35 + 4.14mL/s and post operative peak flow rate was 20.60 +7.77mL/s. There was statistically significant difference between the pre –operative and post-operative peak urine flow rates (t value = 11.12, degree of freedom =20 and P value = 0.00). Twenty five patients (89.3%) had satisfactory voiding by flow rate measurement and subjective symptom assessment after urethral catheter removal and at 3 months post surgery. Conclusion: Oral mucosa graft urethroplasty provides satisfactory short term outcome with few minor donor site complications for anterior urethral reconstruction in patients with long-segment urethral stricture