Low birth weight is a global health challenge and presents a serious health burden on the newborn health care delivery in developing countries such as Nigeria. Low birth weight babies (LBW) have an increased risk of neonatal morbidity and mortality, and indeed LBW is the single most important risk factor for neonatal death. The birth weight and incidence of low birth weight (LBW) are reflection of the socio-economic disposition and availability of antenatal care in a country. This was a cross-sectional descriptive, hospital-based study conducted from 7th September, 2016 to 6th February, 2017 to determine the incidence of low birth weight, predispositions, neonatal outcome and predictive anthropometric indices among newborn infants in Katsina metropolis. The bio-data, socio-demographic characteristics, pregnancy history and anthropometric measurements were obtained. A total of 4619 live babies were delivered over the study period out of whom 315 were low birth weight babies. The incidence of LBW was 68 per 1000 live births. Nine hundred and eighty five eligible babies were recruited in the study, which comprised 499 (50.7%) males and 486 (49.3%) females respectively.