One hundred patients who were on highly active antiretroviral treatment (HAART) were examined. CD4+ cell counts, using manual dynabeads method, were performed. The patient’s age group range was between 20-60 years and were randomly selected, 53 were females while 47 were males. Initial testing was at entry i.e. before commencement of HAART and the rest were at 4- monthly intervals for one year. There was a statistically significant increase in CD4+ cell count (P = 0.001) at 16 weeks and 32 weeks over the baseline CD4+cell count. However, 6 patients at 32 weeks did not show any statistically significant increase ( P = 0.7) in the CD4+cell count at 16 weeks. It is possible these patients may have attained their normal CD4+cell counts. There was also a corresponding increase in weight of patients over the same period of study. These results of 94% increase in CD4+ cell count is an indication of the efficacy of HAART in these patients.