Background The shared route of transmission could suggest that many HIV positive clients may also be at risk of HBV and HCV infections. HIV co infection with HBV and or HCV may further worsens the outcome for the mother of the infant with a more rapid clinical and immunological progression. The magnitude of this impact of HIV co infection with HBV and or HCV on pregnancy outcome is an important topic of research. Objectives: The aim of the study is to determine the proportion of Hepatitis B, C among HIV positive pregnant women attending ante natal clinic in JUTH and its satellite PMTCT clinics, the risk factors associated with Hepatitis B, C and HIV co-infection among pregnant women in JUTH and the effects of hepatitis B, C or B & C co-infection with HIV on pregnancy outcome. Methods: A cross sectional study with longitudinal component was carried out among 150 HIV positive pregnant women seen at the PMTCT clinics of Jos University Teaching Hospital. The women were screened for hepatitis B and C virus infection at enrollment, CD4 count levels were also determined. The women were followed up to delivery to evaluate the pregnancy outcome. All relevant data including the socio-demographic information obstetric history, past medical history and risk factors for HBV, HCV and the viral hepatitis results, CD4 counts levels pregnant outcome were collected and analysed using the statistical package for social sciences (SPSS) version 20. Chicago Illinois.