Background Interests in family functioning have been gaining grounds in recent times as the role it plays in overall health is being elucidated. In our local environment not much work has been done in this field. Several studies have shown the relationship between chronic illnesses and Family functioning. This study aims to elucidate family functionality amongst people living with HIV and AIDS. Objectives of the study Family functioning was assessed among a cohort comprised of people living with HIV/AIDS in order to assess for the pattern of functionality, the factors which influence functionality and the relationship between family function and the respondents’ clinical indices Materials and methods This was a cross sectional analytical study. One Hundred and five respondents were randomly selected (using systematic random sampling) from the adult HIV clinic and assessed using the McMasters family assessment device across 7 dimensions of family functioning. The results were collated on a scale of 1 to 4. Scores closer to 1 represented healthier function, while scores close to 4 represented dysfunctionality. Scores above the McMasters family assessment cutoff points were regarded as dysfunctional. Statistical analyses were performed to ascertain the factors which influenced family functioning, and to ascertain the relations with various clinical indices. Results Most respondents had normal functionality in the problem solving and communication dimensions with mean scores of 1.56 and 1.97 respectively. However in the other subscales majority of the respondents had dysfunctional scores; Family roles: 2.42; Affective responsiveness: 3.14; Affective involvement: 3.24; Behaviour control: 2.66. The mean general