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EFFECTS OF SOCIOECONOMIC FACTORS ON IRON STORES AMONG PREGNANT WOMEN IN ILORIN.

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Supervisor: Professor. J. O. Adewuyi, Professor. P. O. Olatunji
Faculty: PATHOLOGY
Month: 11
Year: 2008

Abstract

This study compared the serum ferritin concentrations (sFC) and haematological parameters in anaemic and non anaemic pregnant women (subjects) and non pregnant women (controls). It also went further to determine what effects have socio-demographic factors, such as age, parity, weight, height, and socioeconomic status of participants and their spouses, on iron stores (as indicated by the serum ferritin concentration, sFC) and haematological parameters in anaemic and non anaemic pregnant women. A total of Two Hundred and Forty women, all in the age range 20-44years and made up of 180 otherwise healthy pregnant women (subjects) and 60 apparently healthy non pregnant women (controls) were recruited into this study. Full blood count, Reticulocyte count, serum ferritin concentrations and, stool and urine microscopy were done on samples obtained from both subjects and controls. Seventy percent (70%) of subjects in this study were anaemic as opposed to 15% in controls. Majority(67.8%) of subjects have mild to moderate anaemia while 2.2% had severe anaemia. Eleven of 126 anaemic pregnant women(6.1%) had frank iron deficiency anaemia( low iron stores with subnormal values of red cell indices). The mean serum ferritin concentrations in subjects did not differ significantly from value in controls. Serum ferritin concentrations correlated negatively with haemoglobin concentration in subjects while the correlation between these parameters in controls is positive. This parameter also curiously appear to be increasing as we move down the social ladder in anaemic and non anaemic subjects while the mean Hb is decreasing in this direction. Two subjects (1.1%) and two of controls (3.3%) have Ascaris in their stool while the urine samples of all subjects and controls did not reveal Ova or Cyst of parasites on microscopy. This study has shown that anaemia in pregnancy is still highly prevalent(70%) and severe anaemia still occur in pregnancy. In addition, pregnant women, even when their iron stores are adequate, still become anaemic suggesting that they may be less able to mobilize their stores of iron than their non pregnant counterparts. Also, a possible raised prevalence of sub clinical chronic inflammatory condition as we move down the social ladder may account for the increasing serum ferritin concentration with decreasing Hb in that direction. Infestation by parasite that cause blood loss such as hookworms and Schiztosomes are very rare in participants in this study.

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