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EFFECTS OF MATERNAL HAEMOGLOBIN AND SERUM FERRITIN YEAR SUPERVISOR CONCENTRATIONS IN PREGNANCY ON SOME HAEMATOLOGICAL PARAMETERS OF THE NEWBORN IN BENIN CITY.

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Supervisor: 1. Dr. N.K.D. Halim 2. Dr. A.S.Akanmu,
Faculty: PATHOLOGY
Month: 11
Year: 2006

Abstract

The objective of the study was to determine the effects of maternal haemoglobin and ferritin concentration in pregnancy on some haematological parameters of the newborn at the University of Benin Teaching Hospital, Benin City. Eighty pregnant women were recruited. They were bled at term. Their haemoglobin and serum ferritin levels were determined. The corresponding Cord haematological parameters with serum ferritin were also determined at birth. Information was obtained on social- demographic characteristics of the subjects with the aid of questionnaire after they have signed the informed consent form. Maternal obstetric indices viz- parity and last confinement were also documented .The subjects were subdivided into various age groups-20-24, 25-29,30-34,35-39 and 40-44. The mean maternal haemoglobin level was 11.71±1.3 g/dl. Seven (8.75%) of the eighty women studied were found to be anaemic (i.e. haemoglobin levels less 10g/dl). The mean serum oxically higher than that of the non was found to decrease with increasing maternal age though this did not reach a significant level. F=0.632 and P = 0.641.Likewise MMSFL falls with increasing maternal parity but did not reach a significant level. F=0.086,p=0.986.The closer the period of last confinement to the time of study, the lower the MMSFL, although this relationship did not also reach a significant level. However there was a significant difference between MMSFL of mothers` age group 20 /L) when compared with that of mothers’ age group 35 and mothers’ age group 40-rritin levels of the mothers correlated positively with the haemoglobin concentration and red blood cell counts of their babies(r = 0.295, p = 0.0123 and r = 0.226, p = 0.044 respectively). Other cord haematological parameters (WBC and platelets) did not correlate significantly with the maternal ferritin. Although maternal haemoglobin correlated negatively with Cord ferritin (r = -0.284, p = 0.011) it did not correlate with Cord haemoglobin and the other Cord parameters studied (WBC, RBC and platelets). It was concluded that increasing maternal age affects maternal ferritin and that maternal anaemia may not be a predictor of fetal haemoglobin.

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