BACKGROUND Caesarean section is a commonly performed surgical operation in women and its prevalence is rising each year. Caesarean section is a clean contaminated surgical procedure, the risk of wound complications is less. Dressings are typically left in place for 24- 48 hours post-caesarean section to allow time for healing and reepithelisation but whether removal of dressing less than 24 hours is associated with increased risk of surgical site infections has not yet been determined. AIM The study aimed at comparing the risk of surgical site infections with the timing of removal of wound dressing post-caesarean section in LTH, Ogbomoso, Nigeria. METHODOLOGY Women were recruited from ANC, ANW and in the labour ward of LTH, Ogbomoso with emphasis on voluntary participation. One hundred and fifty women were randomized into 3 groups; 50 women in each of the group, with the first group having their skin wound dressing removed 12 hours post-caesarean section and the second group at the 24 hours post caesarean section while third group at 48 hours post-caesarean section. The instrument of survey was in the form of a proforma and wound scoring system. Analysis of obtained data was done with Statistical Package for Social Sciences (SPSS) version 20. Statistical significance was set at p value less than 0.05(95%CI) and comparison of analysis was done using chi-square.