Introduction: Pre-eclampsia is characterized by profound lipid abnormalities similar to those present in atherosclerosis, such as hypertriglyceridemia and predominance of small dense low density lipoprotein particles which are likely to play a role in endothelial dysfunction and endothelial damage. Pre-eclampsia and atherosclerosis are both endothelial diseases with an important involvement of lipid mediated oxidative damage, and their lipid profiles are remarkably similar. These and other findings have led to the increasingly accepted notion that abnormal lipid metabolism is involved in the pathogenesis of endothelial dysfunction in preeclampsia. Aim: To analyse the lipid profile in pre-eclamptic women and compare with those who are normotensive. Methodology: This was a case-control study involving Pre-eclamptics and Normontensive pregnant women who presented to Usmanu Danfodiyo University Teaching Hospital, Sokoto. One hundred and ten participants were recruited consecutively comprising both cases and controls and a semi structured interviewer administered questionnaire was completed. Fasting venous blood samples were collected following recruitment. The sera were separated and analysed for the following parameters; triglycerides (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL) and high density lipoprotein cholesterol (HDL).