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COMPARATIVE STUDY OF INTERNATIONAL PROSTATE SYMPTOM SCORE AND UROFLOWMETRY IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA AT NNAMDI AZIKIWE UNIVERSITY TEACHING HOSPITAL, NNEWI

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Supervisor: PROF. O.O. MBONU, DR. A.M.E NWOFOR, DR. J.C. ORAKWE
Faculty: SURGERY
Month: 5
Year: 2005

Abstract

A review of the literature reveals that benign prostatic hyperplasia (BPH); a non-malignant enlargement of the prostate is a common disease in men above the age of 50 years. A prospective and comparative study of the presentation, International Prostate Symptom Score (IPSS) and uroflow parameters of 51 adult male patients with lower urinary tract symptoms (LUTS) due to BPH and uroflowparameters was undertaken. An equal number of controls that were matched for age at the Nnamdi Azikiwe University Teaching Hospital (NAUTH) Nnewi were analyzed over an 18 month period. This study confirms the increasing incidence of BPH with age. The highest incidence occurred in the eighth decade of life, with majority of the patients (58.9%) having moderate symptoms on IPSS. The correlation between IPSS and uroflow parameters showed a weak correlation between IPSS and voiding time (r = 0.220, p> 0.05), and flow time (r = 0.128, p>0.05). There was a negative correlation between IPSS and maximum flow rate (r = -0.368, p<0.05), average flow rate (r = -0.203, p>0.05), voided volume (r= -0.164, p>0.05), and time to maximum flow (r= -0.246, p>0.05). This negative correlation was statistically significant for maximum flow rate. This study also highlights the inadequacy of urine flow measurement in the detection of lower urinary tract obstruction (LUTO) due to BPH, as only 33.3% of patients studied had maximum flow rate (Qmax) within the obstructed range. Since there is a negative correlation between IPSS and Qmax, they can both be said to measure different parameters They are both easy to carry out, with the added advantage of non invasiveness of the uroflowmetry.

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