BACKGROUND: Induction of labour is one of the common obstetric interventions and post-dated pregnancy is the commonest indication for this procedure. The favourability of the cervix before initiation of this process increases the chances for vaginal delivery. Over the years the Bishop scoring system had been used but it is known to be subjective due to inter and intraobserver errors. A more objective and reproducible modality for assessment of the favourability of the cervix for labour induction could possibly predict the rapidity of cervical ripening and probable duration of the whole labour process. Hence, fetal fibronectin, a biochemical marker in cervico-vaginal secretion is the focus of this study as a possible predictive tool for cervical ripening time and duration of labour. • OBJECTIVE: To assess the efficacy of cervico-vaginal fetal fibronectin in predicting pre-induction cervical ripening time and the duration of labour in women with post-dated pregnancy and unfavourable cervix scheduled for induction of labour. • METHODOLOGY: This is a descriptive cross-sectional study involving 152 women with post-dated pregnancy scheduled for cervical ripening with transcervical foley catheter and induction of labour at estimated gestational age of 41 weeks + 3 days. Pre-cervical ripening cervico-vaginal swab was taken for quantitative assessment of Fetal fibronectin with enzyme linked immunosorbent assay (ELISA). The duration of time spent for cervical ripening and induction of labour for each subject was correlated with their cervico-vaginal fetal fibronectin levels. SPSS version 19 was used for statistical analysis.