BACKGROUD: Preeclampsia is one of the leading causes of maternal and perinatal morbidity worldwide, especially in developing countries. So far, the aetiopathogenesis has remained unresolved. Calcium, potassium and uric acid are commonly deranged in serum of preeclamptics and are usually associated with poor neonatal outcome. OBJECTIVE: To determine the variations of serum levels of calcium potassium and uric acid among normotensive and preeclamptic patients. STUDY DESIGN: This was a hospital based case control study. METHODOLOGY: Pregnant women with raised blood pressure and significant proteinuria who meet the inclusion criteria from 28 weeks to 42 weeks gestation were recruited as they attended the ante-natal clinic, labour ward or outpatient emergency unit. Each of these patients was matched with a normotensive non-proteinuric pregnant woman for age, gestational age and parity. Socio- demographic variables and clinical characteristics such as age, parity, gestational age at presentation, blood pressure, and degree of proteinuria, levels of maternal serum calcium, potassium and uric acid were then recorded. Patients were followed till delivery and neonatal outcome data collected.