Background: preeclampsia is the most severe form of hypertensive disorder of pregnancy and is associated with maternal and fetal mortality. It is important to predict preeclampsia to allow for adequate surveillance and early detection of disease.The search for biomarkers for predicting preeclampsia is still ongoing. Mean arterial blood pressure (MABP), which has the advantage of presenting a single cutoff value compared with the use of systolic and diastolic blood pressure measurements, merits evaluation. Aim: The study aims to evaluate antenatal mean arterial blood pressure (MABP) in the prediction of preeclampsia among at risk women. Methods: This will be a prospective cohort study of 150 normotensive, nonproteinuric pregnant women. The women will be booked patients attending the antenatal clinic at the University of Abuja Teaching Hospital. The end point of the study will be the development of preeclampsia. The diagnosis of preeclampsia will be made by the attending obstetrician. The data will be analyzed using the IBM SPSS statistical software. Statistical significance will be set at P< 0.05.