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A REVIEW OF COLUMNAR CELL LESIONS IN FIBROCYSTIC CHANGE OF THE BREAST IN LAGOS UNIVERSITY TEACHING HOSPITAL (LUTH); A 10 YEAR RETROSPECTIVE STUDY (JANUARY 2004 TO DECEMBER 2013)

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Supervisor: DR. A.O. DARAMOLA DR.M. O. ODUBANJO PROF. A.A.F. BANJO
Faculty: PATHOLOGY
Month: 11
Year: 2014

Abstract

Background: Columnar cell lesions (CCLs) of the breast are now gaining clinical attention because of the increasing use of mammographic screening as one of the breast cancer prevention strategies. Columnar cell lesions are important because certain variants may be precursors of low-grade ductal carcinoma in situ (DCIS). In Nigeria and much of the developing world, mammography is novel and CCLs have not been studied among the black populations as a result Objectives: We set out to find out whether CCLs occur among Nigerian women and, if so, to estimate their frequency of occurrence of CCLs, using fibrocystic change (FCC) as a surrogate lesion so as offer us a peep into its real prevalence in the wider women population. We also set out to determine the range of CCLs found using the recognized histologic criteria Materials and methods: We studied all consecutive breast biopsies that were diagnosed with FCC within a 10-year period at the department of Anatomic and molecular Pathology LUTH.

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