Background: Labour is generally considered to be a very painful experience. Epidural analgesia which is the gold standard for labour pain relief is not widely available, affordable or feasible especially in our environment. Parenteral opioid analgesics, which are more commonly used, can cause nausea and vomiting in the patient and respiratory depression in the neonate, hence they cannot be used in all stages of labour. There is thus the need for an alternative analgesic with similar or superior analgesic effect to opioids but without their fetomaternal side effects. Objectives: To compare the efficacy of intramuscular pentazocine and intravenous paracetamol infusion in relieving labour pain at Aminu Kano Teaching Hospital, Kano. Study Design: It was a prospective randomised controlled study. Methods: One hundred women with singleton uncomplicated pregnancies and spontaneous labour at term were randomly assigned to the study group or control group. Women in the study group received an intravenous infusion of 1000mg of paracetamol while women in the control group received a single dose of 30 mg of pentazocine intramuscularly. Labour pain perception was assessed using VAS scores at presentation and after delivery while maternal satisfaction assessed using Likert scale, and maternal and fetal complications were recorded after delivery. Statistical analysis was done using computer software SPSS Version 20.0. Chi-square, Fisher’s exact test, t-test and Mann-Whitney U-tests were used to compare means and proportions as appropriate for statistically significant differences, setting the level of significance (P-value) at < 0.05.